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KMID : 1039620210110030210
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Korean Journal of Family Practice
2021 Volume.11 No. 3 p.210 ~ p.216
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Prevalence of Respiratory Viral Infection Using Multiplex Reverse Transcriptase-Polymerase Chain Reaction
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Kim Jun-Seok
Kim Jae-Min
Choi Sik-Kyung
Cho Yeon-Jong
Kim Su-Jung
Kim Jung-Are
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Abstract
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Background: We wanted to understand the prevalence of respiratory viral infections in children hospitalized for acute respiratory infections stratified by sex, age, season, multiple infections, and clinical symptoms.
Methods: Out of 1,331 children hospitalized for acute respiratory infections who underwent the multiplex reverse transcriptase-polymerase chain reaction test between October 2015 and June 2017, viral infections were detected in 921, and these were included in the study.
Results: Of the 1,331 patients, 667 (50.1%) were males with a median age of 55 months. Of the 921 (69.2%) children with viral infections, 443 (48.1%) were males, and there was no statistically significant sex-related difference. Additionally, 698 (52.4%) were infected by a single virus: 194 cases of human rhinovirus (HRV) (14.6%), 181 cases of adenovirus (ADV) (13.6%), and 159 cases of respiratory syncytial virus B (RSV B) (11.9%). Infections by two or more viruses were detected in 222 cases (24.1%). The common combinations of viruses were HRV and ADV in 37 (16.7%) cases, RSV A and ADV in 17 cases (7.7%), and RSV A and RSV B in 15 cases (6.8%). Regarding the seasonal patterns, HRVs and ADVs were detected throughout the year. Metapneumoviruses were detected more often during spring, and RSVs were detected more often in November and December.
Conclusion: The prevalence of respiratory viral infections in a single center was analyzed during 21 months, and the results of this analysis may be useful for epidemiology and the treatment and prevention of acute respiratory infections.
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KEYWORD
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Respiratory Virus, Multiplex Polymerase Chain Reaction, Prevalence, Children
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